Neuropharmacology and Neurochemistry

Neurochemical Mechanisms in Neurodegenerative Disorders

This session investigates the complex neurochemical pathways involved in neurodegenerative diseases such as Alzheimer’s, Huntington’s, and Parkinson’s disease. The progressive loss of neuronal integrity is closely linked to disruptions in neurotransmitter metabolism, oxidative stress, and mitochondrial dysfunction. Neuropharmacological studies have revealed the roles of dopamine, acetylcholine, glutamate, and serotonin in neuronal survival and synaptic plasticity. Participants will examine recent advances in pharmacological agents designed to counteract neurotoxicity and enhance neuroprotection. Emphasis will be placed on identifying biomarkers for early diagnosis and the therapeutic potential of compounds targeting amyloid aggregation and tau phosphorylation. This discussion promotes new directions for restoring chemical balance and neuronal resilience in degenerative conditions.