Neuropharmacology and Neurochemistry

Neuropharmacological Approaches to Pain Modulation and Analgesia

Pain perception is governed by intricate neurochemical processes within the central and peripheral nervous systems. This session focuses on the neuropharmacological basis of pain modulation and the mechanisms through which analgesic agents alter neural signaling. It highlights the role of neurotransmitters such as substance P, glutamate, and gamma-aminobutyric acid in pain transmission and inhibition. Discussions will cover opioid and non-opioid receptor systems, receptor desensitization, and the development of new pharmacological compounds with reduced addiction potential. Exploring the relationship between neurochemical regulation and pain pathways, this topic emphasizes innovative strategies to achieve safe and effective analgesia without compromising brain function.